2000: The Saudi Student Association is established
2000: Sharifa Charlery, class of 2000 and a recipient of the Kaufman Award for leadership and service to the Old Domination community, becomes the first female African American Student Body President
2000: Sister4Sister student organization is created to address the cultural, social, and academic needs of African American female students.
2001: The African Caribbean Association is established
July 2001: Roseann Runte, President of Victoria University in Toronto, Canada, becomes the seventh and first female president of Old Dominion
2002: The Institute of Jewish Studies and Interfaith Understanding is established. The institute seeks to foster knowledge of Jewish history and cultures, and through scholarship, education and community outreach
2002: The Gay Lesbian Bisexual Students and Allies organization changes its name to the ODU Out Student Alliance, and later to ODU Out
2002: The Omega chapter of Sigma Lambda Upsilon becomes the first Latina sorority on campus
2004: A major and minor in Asian Studies is offered for the first time
2005: The Latino Student Alliance is established as a multi-ethnic organization dedicated to unifying students from all backgrounds while appreciating and connecting with the Hispanic ethnicity.
2005: The Global Student Friendship organization, aimed at welcoming international students and scholars to the Old Dominion campus by providing events, tours, and other services, is established
2006: The Safe Space Committee, aimed at raising awareness and tolerance for the LGBTQ community at Old Dominion, is established
2006: F.O.R.E.I.G.N.E.R.S., a student organization created to help welcome the international community to Old Dominion, is established during the 2006-2007 academic year
2007: Lambda Upsilon Lambda becomes the first Latino fraternity on campus. The Old Dominion chapter, however, is a multicultural chapter.
2007: Old Dominion unveils a new Bachelor of Arts degree in African American and African Studies (AAST) program
2008: The Office of Equal Opportunity and Affirmative Action restructures into the Office of Institutional Equity and Diversity to adequately prioritize Old Dominion's commitment to diversity and inclusion. ReNee Dunman serves as the office's director
2008: The Office of Intercultural Relations, geared toward creating a community that is supportive of and values all cultures at Old Dominion, is created with Lesa Clark as the first Assistant Dean of Intercultural Relations